Iranian Veterinary Journal

Iranian Veterinary Journal

The Effects of probiotic Saccharomyces cerevisiae and Lactobacillus rhamnosus on the growth factors and serum biochemistry of Oreochromis niloticus

Document Type : Research Paper

Authors
Marzieh Mohammadpoor 1
Rahim Peyghan 2
Seyedeh Misagh Jalali 3
Zahra Basir 4
Takavar Mohammadian 2
1 PhD Student of Fish Health and Diseases, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran
2 Professor, Department of Livestock, Poultry and Aquatic Animal Health, Faculty of Veterinary Medicine Shahid Chamran University of Ahvaz, Ahvaz, Iran and Member of Excellence Center of Warm Water Fish Health, Shahid Chamran University of Ahvaz, Ahvaz, Iran
3 Associate Professor, Department of Clinical Science, Faculty of Veterinary Medicine, Shahaid Chamran University of Ahvaz, Ahvaz, Iran
4 Associate Professor, Department of Basic Sciences, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran
10.22055/ivj.2025.509224.2780
Abstract
    In this study, the effects of a feeding combination of Saccharomyces cerevisiae and Lacticaseibacillus rhamnosus on the growth and serum biochemical indices of Nile tilapia (Oreochromis niloticus) was investigated. For this purpose, a total of 300 Nile tilapia were divided into 10 groups (average weight: 20±7 g) and fed diets containing varying levels of yeast and bacteria for 60 days (30 fish in each treatment group, 10 fish in three replicates). Bacterial strain identification was performed using phenotypic, biochemical, and genetic characteristics. The control group was fed a commercial diet without the selected probiotic strains. Group 1 received only the bacterial strain, while groups 2 to 5 were fed diets containing different doses of yeast supplementation. Groups 6 to 9 received a combination of bacteria and yeast (commercial diet + 0.25%, 0.5%, 1%, and 1.5% yeast + bacteria). At the end of the trial, growth performance and serum biochemical parameters were analyzed. The results showed that the combination of these two probiotics improved the growth indices and the increased survival rates in fish. Additionally, significant changes were observed in some biochemical parameters, including an increase in HDL levels and glucose in yeast-fed groups that reflects the stress response. Instead of changes in biochemical results, based on the growth factors at the end of the study, a combination of S.cerevisiae and probiotic L.rhamnosus is a  nutritional strategy for enhancing aquatic health and performance.
Keywords
Probiotics
Lacticaseibacillus rhamnosus
Saccharomyces cerevisiae
Fish growth
Serum biochemical indices
Oreochromis niloticus

Subjects

 
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