Histopathologic patterns of nontumoric cutaneous lesions in dogs referred to Veterinary Hospital of Ahvaz

Document Type : Research Paper

Authors

1 DVM Graduated from Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran

2 Associate Professor, Department of pathobiology, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran

3 Professor, Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran

Abstract

The aim of this study is inspection of histopathologic patterns in skin lesions of referred dogs to Veterinary Hospital of Shahid Chamran University. This study carried out on 40 cases. After complete macroscopic examination and sedation, sampling was carried out and Haematoxylin and Eosin stained slides were prepared. In macroscopic examination all cases had alopecia and hypotrichosis and 30 (75%) cases had focal alopecia and 10 (25%) had diffuse alopecia. Seventeen cases (42.5%) had seborrhea and 19 (47.5%) had scale and wound. Microscopic examination revealed perivascular dermatitis pattern in 16 (40%) and 12 cases had chronic perivascular dermatitis. Nodular and diffuse dermatitis were seen in 1 and 5 respectively (15%). In two cases of diffuse dermatitis, mite sections were observed. Atrophic dermatitis was detected in 15 cases (37.5%). Perifolliculitis were seen in 18 (45%) and folliculitis were seen in 7 cases (17.5%) and 5 were luminal and 2 were luminal and mural. Furunculosis was seen in one dog (2.5%). Fibrosing dermatitis was detected in 2 (5%) samples. Vasculitis was seen in one dog (2.5%). In this study perivascular dermatitis had the most frequency and it may be due to different agents. Atrophic dermatoses are in second rank and malnutrition is first candidate cause. This study is the first attempt in the field of dermatopathology and the results of present research revealed different type of microscopic patterns.

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راد، محمدعلی؛ جمشیدی، شهرام و ال­داوود، سیدجاوید (1376). بیماری‌های پوست دام‌های کوچک (عفونی و ایمونولوژیک). تالیف: مولر، کرک و اسکات، چاپ اول، انتشارات دانشگاه تهران، تهران، صفحات 322-204.
یوسفی، علیرضا؛ سهرابی‌حق­دوست، ایرج و صداقت، رضا (1389). مطالعه هیستوپاتولوژیک الگوهای رایج ضایعات غیرنئوپلاستیک پوست در سگ. پاتوبیولوژی مقایسه­ای، دوره 7، شماره 3، صفحات 328-321.‎
Ali, M.H.; Begum, N.; Azam, M.G. and Roy, B.C. (2011). Prevalence and pathology of mite infestation in street dogs at Dinajpur municipality area. Journal of Bangladesh Agricultural University, 9(1): 111-119.
Bertolino, A.P. and Freedberg, I.M. (1987). Disorders of epidermal appendages and related disorders: Hair. Dermatology in General Medicine. In Fitzpatrick, T.B.; Eisen, A.Z.; Wolff, K.; Freedberg, I.M. and Austen, K.F. (Eds). Dermatology in General Medicine. New York: McGraw-Hill Book Company, Pp: 639-640.
Bratka-Robia, C.B.; Egerbacher, M.; Helmreich, M.; Mitteregger, G.; Benesch, M. and Bamberg, E. (2002). Immunohistochemical localization of androgen and oestrogen receptors in canine hair follicles. Veterinary Dermatology, 13(2): 113-118.
Caswell, J.L.; Yager, J.A.; Parker, W.M. and Moore, P.F. (1997). A prospective study of the immunophenotype and temporal changes in the histologic lesions of canine demodicosis. Veterinary Pathology Online, 34(4): 279-287.
Foster, A.P. (2006). Cutaneous manifestations of vasculitis in the dog. Companion Animal, 11(6): 71-77.
Foster, A.P. and Foil, C.S. (2003). BSAVA manual of small animal dermatology. British Small Animal Veterinary Association, 2nd ed, Pp: 159-160.
Ginn, P.E.; Mansell, J.E.K.L. and Rakich, P.M. (2007). Skin and Appendages. In: Maxie, M. G. Jubb, Kennedy and Palmer's Pathology of Domestic Animal. Vol. 1, 5th Ed, Saunders, Elsevier Philadelphia, Pp: 553-781.
Hargis, A.M. and Ginn, P.E. (2012). Integumentary system.In: McGavin, M.D. and Zachary, J.F. (Eds), Pathologic Basis of Veterinary Disease. 5th Ed, Elsevier, China, Pp: 972-1084.
Hill, P.B. and Olivry, T. (2001). The ACVD task force on canine atopic dermatitis (XVIII): histopathology of skin lesions. Veterinary Immunology and Immunopathology, 81(3-4): 305-309.
Holm, B.R.; Rest, J.R. and Seewald, W. (2004). A prospective study of the clinical findings, treatment and histopathology of 44 cases of pyotraumatic dermatitis. Veterinary Dermatology, 15(6): 369-376.
Islam, M.M.; Khanam, S.S.; Rashid, S.M.H. and Islam, M.N. (2013). Prevalence and pathology of demodectic mange in stray dogs in Bangladesh. Journal of Science and Technology, Pp: 118-121.
Khoshnegah, J. and Pakzad Shahabi, M. (2009). Canine atopic/allergic dermatitis in Mashhad (North-East of Iran): clinical observations. Iranian Journal of Veterinary Research, 10(4): 352-359.
Mackel, S.E. and Jordon, R.E. (1982). Leukocytoclastic vasculitis a cutaneous expression of immune complex disease. Archives of Dermatology,118(5): 296-301.
Medleau, L. and Hnilica, K.A. (2001). Keratinization and seborrheic disorders. Small Animal Dermatology: A Color Atlas and Therapeutic Guide, WB Saunders, Philadelphia, Pp: 215-237.
Nichols, P.R.; Morris, D.O. and Beale, K.M. (2001). A retrospective study of canine and feline cutaneous vasculitis. Veterinary Dermatology, 12(5): 255-264.
Tasaki, Y.; Miura, N.; Iyori, K.; Nishifuji, K.; Endo, Y. and Momoi, Y. (2013). Generalized alopecia with vasculitis-like changes in a dog with babesiosis. The Journal of Veterinary Medical Science, 75(10): 1367-1369.
Walder, E.J. (1992). Atrophic Diseases of The Hair Follicle In: Gross, T.L.; Ihrke, P.J. and Walder, E.J. (Eds), Veterinary Dermatopathology: A Macroscopic and Microscopic Evaluation of Canine and Feline Skin Disease. Mosby-Year book, United States of America, Pp: 273-297.