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<!DOCTYPE ArticleSet PUBLIC "-//NLM//DTD PubMed 2.7//EN" "https://dtd.nlm.nih.gov/ncbi/pubmed/in/PubMed.dtd">
<ArticleSet>
<Article>
<Journal>
				<PublisherName>دانشگاه شهید چمران اهواز</PublisherName>
				<JournalTitle>نشریه دامپزشکی ایران</JournalTitle>
				<Issn>1735-6873</Issn>
				<Volume>21</Volume>
				<Issue>2</Issue>
				<PubDate PubStatus="epublish">
					<Year>2025</Year>
					<Month>08</Month>
					<Day>23</Day>
				</PubDate>
			</Journal>
<ArticleTitle>Evaluation of local or intravenous administration of dexamethasone on brachial plexus block with lidocaine in sheep</ArticleTitle>
<VernacularTitle>ارزیابی تجویز داخل وریدی یا موضعی دگزامتازون بر بلوک شبکه­ بازویی با لیدوکائین در گوسفند</VernacularTitle>
			<FirstPage>32</FirstPage>
			<LastPage>40</LastPage>
			<ELocationID EIdType="pii">232509</ELocationID>
			
<ELocationID EIdType="doi">10.22055/ivj.2025.481605.2741</ELocationID>
			
			<Language>FA</Language>
<AuthorList>
<Author>
					<FirstName>پروانه</FirstName>
					<LastName>صادقی</LastName>
<Affiliation>دانش آموخته دکتری حرفه‌ای، دانشکده دامپزشکی، دانشگاه شهید چمران اهواز، اهواز، ایران</Affiliation>

</Author>
<Author>
					<FirstName>هادی</FirstName>
					<LastName>ایمانی راستابی</LastName>
<Affiliation>دانشیار گروه علوم درمانگاهی، دانشکده دامپزشکی، دانشگاه شهید چمران اهواز، اهواز، ایران</Affiliation>
<Identifier Source="ORCID">0000-0002-1564-7240</Identifier>

</Author>
<Author>
					<FirstName>معصومه</FirstName>
					<LastName>عزتی گیوی</LastName>
<Affiliation>استادیار گروه علوم پایه، دانشکده دامپزشکی، دانشگاه شهید چمران اهواز، اهواز، ایران</Affiliation>

</Author>
<Author>
					<FirstName>کاوه</FirstName>
					<LastName>خزائیل</LastName>
<Affiliation>دانشیار گروه علوم پایه، دانشکده دامپزشکی، دانشگاه شهید چمران اهواز، اهواز، ایران</Affiliation>
<Identifier Source="ORCID">0000-0002-4505-1106</Identifier>

</Author>
</AuthorList>
				<PublicationType>Journal Article</PublicationType>
			<History>
				<PubDate PubStatus="received">
					<Year>2024</Year>
					<Month>10</Month>
					<Day>03</Day>
				</PubDate>
			</History>
		<Abstract>&lt;span style=&quot;font-size: 10.0pt; mso-bidi-font-family: &#039;B Lotus&#039;; background: white;&quot;&gt;&lt;span style=&quot;mso-spacerun: yes;&quot;&gt;    &lt;/span&gt;This study aimed to determine the effect of adding dexamethasone topically and intravenously on the onset and duration of sensory and motor blocks following brachial plexus block in sheep. In the present study, 20 adult female Arab sheep with an average weight of 32.9 ± 3.4 kg were used. To provide a brachial plexus block, the sheep were randomly assigned to one of three treatments of lidocaine (LID, 4 mg/kg), topical lidocaine- topical dexamethasone (LIDEXL, 4 mg/kg and 8 mg), and topical lidocaine- intravenous dexamethasone (LIDEXV, received 4 mg/kg and 8 mg). In the third group, dexamethasone was injected intravenously 10 minutes before anesthesia application. To identify the nerves, an electrical nerve stimulator was used. With nerve stimulation, the contraction and movements of the limbs were observed, and the drug was injected into the site until the limb movement stopped. The results showed that the onset of radial nerve block in the LIDEXL group was significantly lower than that of lidocaine alone. The duration of sensory and motor blocks was 68.11 ± 23.67 and 75.00 ± 30.41 minutes in the LID group; 59.6 ± 18.12 and 81.17 ± 20.90 minutes in the LIDEXL group, and 62.58 ± 16.55 and 64.40 ± 16.83 minutes in the LIDEXV group. No significant difference was observed between the groups. According to the results, adding dexamethasone topically and intravenously to lidocaine does not affect the onset or duration of sensory and motor nerve blocks following a brachial plexus block in sheep.&lt;/span&gt;</Abstract>
			<OtherAbstract Language="FA">&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;B Yagut&#039;; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; color: windowtext;&quot;&gt;&lt;span style=&quot;mso-spacerun: yes;&quot;&gt;    &lt;/span&gt;هدف از مطالعه حاضر، اثر افزودن دگزامتازون به صورت موضعی و وریدی بر زمان شروع و طول دوره‌ بلوک اعصاب، متعاقب بلوک شبکه بازویی گوسفندان تعیین شد. &lt;span style=&quot;mso-spacerun: yes;&quot;&gt; &lt;/span&gt;در مطالعه‌‌ حاضر 20 رأس گوسفند ماده بالغ از نژاد عرب با میانگین وزنی 4/3 &lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;Cambria&#039;,serif; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; mso-bidi-font-family: Cambria; color: windowtext;&quot;&gt;±&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;B Yagut&#039;; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; color: windowtext;&quot;&gt; 9/32 کیلوگرم مورد استفاده قرار گرفتند. &lt;span style=&quot;mso-spacerun: yes;&quot;&gt; &lt;/span&gt;به منظور ایجاد بلوک شبکه‌‌ بازویی، گوسفندان به صورت تصادفی یکی از سه درمان لیدوکائین (&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size: 10.0pt; font-family: &#039;Times New Roman&#039;,serif; mso-bidi-font-family: &#039;B Yagut&#039;; color: windowtext;&quot;&gt;LID&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;B Yagut&#039;; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; color: windowtext;&quot;&gt;، &lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size: 10.0pt; font-family: &#039;Times New Roman&#039;,serif; mso-bidi-font-family: &#039;B Yagut&#039;; color: windowtext;&quot;&gt;mg/kg&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;B Yagut&#039;; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; color: windowtext;&quot;&gt; 4)، لیدوکائین- دگزامتازون موضعی (&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size: 10.0pt; font-family: &#039;Times New Roman&#039;,serif; mso-bidi-font-family: &#039;B Yagut&#039;; color: windowtext;&quot;&gt;LIDEXL&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;B Yagut&#039;; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; color: windowtext;&quot;&gt; ،&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size: 10.0pt; font-family: &#039;Times New Roman&#039;,serif; mso-bidi-font-family: &#039;B Yagut&#039;; color: windowtext;&quot;&gt;mg/kg&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;B Yagut&#039;; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; color: windowtext;&quot;&gt; 4 و &lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size: 10.0pt; font-family: &#039;Times New Roman&#039;,serif; mso-bidi-font-family: &#039;B Yagut&#039;; color: windowtext;&quot;&gt;mg&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;B Yagut&#039;; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; color: windowtext;&quot;&gt; 8) و لیدوکائین- دگزامتازون وریدی (&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size: 10.0pt; font-family: &#039;Times New Roman&#039;,serif; mso-bidi-font-family: &#039;B Yagut&#039;; color: windowtext;&quot;&gt;LIDEXV&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;B Yagut&#039;; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; color: windowtext;&quot;&gt; ،&lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size: 10.0pt; font-family: &#039;Times New Roman&#039;,serif; mso-bidi-font-family: &#039;B Yagut&#039;; color: windowtext;&quot;&gt;mg/kg&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;B Yagut&#039;; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; color: windowtext;&quot;&gt; 4 و &lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size: 10.0pt; font-family: &#039;Times New Roman&#039;,serif; mso-bidi-font-family: &#039;B Yagut&#039;; color: windowtext;&quot;&gt;mg&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;B Yagut&#039;; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; color: windowtext;&quot;&gt; 8) را دریافت کردند. &lt;span style=&quot;mso-spacerun: yes;&quot;&gt; &lt;/span&gt;در گروه سوم، دگزامتازون 10 دقیقه قبل از تجویز بی‌‌حسی‌‌، به صورت وریدی در ورید وداج تزریق شد. &lt;span style=&quot;mso-spacerun: yes;&quot;&gt; &lt;/span&gt;به منظور شناسایی اعصاب از دستگاه تحریک عصب استفاده ‌‌شد. &lt;span style=&quot;mso-spacerun: yes;&quot;&gt; &lt;/span&gt;با تحریک عصبی، انقباض و حرکات اندام مشاهده گردید و دارو در محل تا زمان قطع حرکت اندام تزریق شد. &lt;span style=&quot;mso-spacerun: yes;&quot;&gt; &lt;/span&gt;نتایج نشان داد که زمان شروع بی­حسی عصب زندزبرینی در گروه &lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size: 10.0pt; font-family: &#039;Times New Roman&#039;,serif; mso-bidi-font-family: &#039;B Yagut&#039;; color: windowtext;&quot;&gt;LIDEXL&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;B Yagut&#039;; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; color: windowtext;&quot;&gt; به صورت معنی­ داری پایین‌تر از لیدوکائین تنها بود. &lt;span style=&quot;mso-spacerun: yes;&quot;&gt; &lt;/span&gt;مدت زمان بی­حسی و بی­حرکتی در گروه &lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size: 10.0pt; font-family: &#039;Times New Roman&#039;,serif; mso-bidi-font-family: &#039;B Yagut&#039;; color: windowtext;&quot;&gt;LID&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;B Yagut&#039;; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; color: windowtext;&quot;&gt;، به ترتیب برابر با 67/23 &lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;Cambria&#039;,serif; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; mso-bidi-font-family: Cambria; color: windowtext;&quot;&gt;±&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;B Yagut&#039;; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; color: windowtext;&quot;&gt; 11/68 و 41/30 &lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;Cambria&#039;,serif; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; mso-bidi-font-family: Cambria; color: windowtext;&quot;&gt;±&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;B Yagut&#039;; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; color: windowtext;&quot;&gt; 00/75 دقیقه؛ در گروه &lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size: 10.0pt; font-family: &#039;Times New Roman&#039;,serif; mso-bidi-font-family: &#039;B Yagut&#039;; color: windowtext;&quot;&gt;LIDEXL&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;B Yagut&#039;; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; color: windowtext;&quot;&gt;، به ترتیب برابر با 12/18 &lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;Cambria&#039;,serif; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; mso-bidi-font-family: Cambria; color: windowtext;&quot;&gt;±&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;B Yagut&#039;; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; color: windowtext;&quot;&gt; 6/59 و 90/20 &lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;Cambria&#039;,serif; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; mso-bidi-font-family: Cambria; color: windowtext;&quot;&gt;±&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;B Yagut&#039;; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; color: windowtext;&quot;&gt; 17/81 دقیقه؛ در گروه &lt;/span&gt;&lt;span dir=&quot;LTR&quot; style=&quot;font-size: 10.0pt; font-family: &#039;Times New Roman&#039;,serif; mso-bidi-font-family: &#039;B Yagut&#039;; color: windowtext;&quot;&gt;LIDEXV&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;B Yagut&#039;; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; color: windowtext;&quot;&gt;، به ترتیب برابر با 55/16 &lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;Cambria&#039;,serif; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; mso-bidi-font-family: Cambria; color: windowtext;&quot;&gt;±&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;B Yagut&#039;; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; color: windowtext;&quot;&gt; 58/62 و 83/16 &lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;Cambria&#039;,serif; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; mso-bidi-font-family: Cambria; color: windowtext;&quot;&gt;±&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;font-size: 10.0pt; font-family: &#039;B Yagut&#039;; mso-ascii-font-family: &#039;Times New Roman&#039;; mso-hansi-font-family: &#039;Times New Roman&#039;; color: windowtext;&quot;&gt; 40/64 دقیقه بود که تفاوت معنی‌داری بین گروه‌ها مشاهده نشد. &lt;span style=&quot;mso-spacerun: yes;&quot;&gt; &lt;/span&gt;با توجه به نتایج این مطالعه، افزودن دگزامتازون به صورت موضعی و وریدی به داروی لیدوکائین تأثیری بر شروع اثر بی­حسی و طول دوره­ بی­حسی موضعی متعاقب بلوک شبکه­ بازویی در گوسفند ندارد.&lt;/span&gt;</OtherAbstract>
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			<Param Name="value">بلوک شبکه‌ی بازویی</Param>
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			<Param Name="value">دگزامتازون</Param>
			</Object>
			<Object Type="keyword">
			<Param Name="value">لیدوکائین</Param>
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			<Object Type="keyword">
			<Param Name="value">گوسفند</Param>
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