Survey on the tetracycline and oxytetracycline residues from collected milk centers of Guilan by HPLC method

Document Type : Case report

Author

Veterinary Department

Abstract

    Due to the harmful effects of antibiotics residues on human health, it is important to monitor their residues in foods. In this study, 15 milk samples have gathered randomly of 4 collected milk centers with containing 4000 liter in 15 different times and samples were referred to lab for HPLC test. Eighty Percent out of total samples were contaminated with tetracycline and oxytetracycline. Tewenty Percent of samples were negative to them. In 26.5% of samples were contaminated to both of them and 53.5% of samples were contaminated only to one antibiotic. HPLC method showed that tetracycline and oxytetracycline residues mean in cow milk were 0.588 µg/ml and 0.722 µg/ml respectively and both of them were contaminated more than maximum residue level limit (MRL). Statistically, there was no significantly different between mean of antibiotics (p>0.05). on the basis results of this research, monitoring  of antibiotic residues in raw milk, control  and minimize  these kinds of contamination  is  necessary for human health. 

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